Tophaceous gout of the first costochondral junction in a heart transplant patient

Tocilizumab in a patient with tophaceous gout resistant to treatment.

Gout is a disease characterized by acute episodes of pain, which occurs as the result of monosodic urate crystal deposit in the joint and periarticular tissue. In some cases, gout behaves as a severe inflammatory arthopathy that is difficult to manage, generating structural joint damage and functional impairment. We report the case of a 44 years old man with gouty arthritis for 12 years, not re...

Tophaceous pustule-like rash in a patient with gout.

Ulcerated tophaceous gout.

Gout is often considered a disease of an excessive lifestyle, a 'malady of kings'. Today, more than 1% of the European and US populations are afflicted with gout, although ulceration over gout tophi remains uncommon. We describe four cases of ulceration associated with gout tophi to highlight the clinical presentation, complications and a management strategy.

Chronic tophaceous gout.

A 44 year old man presented with a 15-day history of painful swelling of right middle finger, which was also red, warm, and tender. A tooth paste like, chalky substance was expressible on pressure from the swelling. The patient reported that he had occasional episodes of joint pains involving both small and large joints of the extremities. He denied a history of medication intake and past histo...

[Chronic tophaceous gout].

A 51-year-old immigrant from the Caucasus had had chronic tophaceous gout for over 20 years, but had never been treated with anti-hyperuricemic drugs. He had developed large, multiple tophi in many locations, including both ankles and feet. The enormous size and unique location of the tophi caused considerable pain, and difficulty in standing and on walking. Since surgical removal of the tophi ...